📚 Wiki Longevity & Anti-Aging

Longevity & Anti-Aging

Longevity, skin, epigenetic, bone health

102 compounds
MOTS-c
MOTS-c is a 16-amino acid mitochondrial-derived peptide (MDP) encoded within the 12S ribos…
NAD+
NAD+ (Nicotinamide Adenine Dinucleotide) is a fundamental coenzyme found in every living c…
L-Carnitine
L-Carnitine (Levocarnitine) is a naturally occurring quaternary ammonium compound synthesi…
Methylcobalamin
Methylcobalamin is the biologically active, methyl-group-carrying form of Vitamin B12 (cob…
GHK-Cu
GHK-Cu (Glycine-Histidine-Lysine Copper Complex) is a naturally occurring tripeptide with …
Ipamorelin
Ipamorelin is a synthetic pentapeptide growth hormone releasing peptide (GHRP) that select…
CJC-1295
CJC-1295 is a synthetic analog of growth hormone releasing hormone (GHRH) engineered with …
Epithalon
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal…
Thymosin Alpha-1
Thymosin Alpha-1 (TA1) is a 28-amino acid peptide naturally secreted by thymic epithelial …
SS-31
SS-31 (Elamipretide) is a synthetic aromatic-cationic tetrapeptide that selectively concen…
Sermorelin
Sermorelin is a synthetic analog of the first 29 amino acids of endogenous GHRH, retaining…
Humanin
Humanin is a 21-amino acid mitochondrial-derived peptide (MDP) encoded within the 16S ribo…
Follistatin-344
Follistatin-344 is a splice variant of follistatin, a naturally occurring glycoprotein th…
AICAR
AICAR (Acadesine) is a cell-permeable adenosine analog that is phosphorylated intracellula…
Pinealon
Pinealon is a synthetic tripeptide (Glu-Asp-Arg) developed by Professor Vladimir Khavinson…
Thymulin
Thymulin (FTS) is a zinc-dependent nonapeptide hormone produced exclusively by thymic epit…
Cortagen
Cortagen (Ala-Glu-Asp-Leu) is a synthetic tetrapeptide from the Khavinson short peptide bi…
Thymalin
Thymalin is a polypeptide extract prepared from bovine thymic tissue containing a mixture …
Vilon
Vilon (Lys-Glu) is a synthetic dipeptide bioregulator developed by Vladimir Khavinson and …
GDF-11
Growth Differentiation Factor 11 (GDF-11) is a member of the TGF-beta superfamily that gai…
Livagen
Livagen is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) developed within Vladimir Khavinson'…
N-Acetyl Epithalon Amidate
N-Acetyl Epithalon Amidate is a chemically modified form of Epithalon (Ala-Glu-Pro-Gly) in…
Vesugen
Vesugen is a synthetic tripeptide bioregulator (Lys-Glu-Asp) developed by Vladimir Khavins…
Chonluten
Chonluten is a synthetic tripeptide bioregulator (Gly-Glu-Pro) developed by Vladimir Khavi…
Normoftal
Normoftal is an oral dipeptide cytogen developed by Vladimir Khavinson's group at the St. …
Carnosine
L-Carnosine (beta-alanyl-L-histidine) is an endogenous dipeptide found in high concentrati…
Cartalax
Cartalax is a synthetic tripeptide bioregulator (Ala-Glu-Asp) developed by Vladimir Khavin…
EGF
Epidermal Growth Factor (EGF) is a 53-amino acid peptide and one of the founding members o…
Argireline
Argireline (acetyl hexapeptide-3, brand name Argireline from Lipotec/Lubrizol) is a synthe…
Snap-8
Snap-8 (Acetyl Octapeptide-3) is a synthetic cosmetic peptide that extends the pharmacopho…
Calcitonin
Calcitonin is a 32-amino acid peptide hormone produced by parafollicular C cells of the th…
GIP
Glucose-dependent insulinotropic peptide (GIP) is a 42-amino-acid incretin hormone secrete…
Apelin-13
Apelin-13 is the most biologically active isoform of the apelin peptide family, endogenous…
Irisin
Irisin is a hormone-like myokine released from skeletal muscle during exercise, generated …
FGF-21
Fibroblast Growth Factor 21 (FGF-21) is an endocrine member of the FGF superfamily that fu…
Bombesin
Bombesin is a 14-amino acid neuropeptide originally isolated from the skin of the European…
FGF-23
Fibroblast Growth Factor 23 (FGF-23) is a 32 kDa endocrine hormone secreted primarily by o…
Osteocalcin
Osteocalcin is a 49-amino acid protein produced by osteoblasts and odontoblasts that was l…
Preptin
Preptin is a 34-amino acid peptide co-secreted with insulin and amylin from pancreatic bet…
CNP
C-Type Natriuretic Peptide (CNP) is a member of the natriuretic peptide family alongside A…
Teriparatide
Teriparatide is the recombinant N-terminal 34-amino acid fragment of human parathyroid hor…
Palmitoyl Pentapeptide-4
Palmitoyl pentapeptide-4 (Matrixyl, pal-KTTKS) is a lipopeptide composed of a palmitoyl fa…
Afamelanotide
Afamelanotide is a synthetic 13-amino acid superagonist analogue of alpha-melanocyte-stimu…
Abaloparatide
Abaloparatide (Tymlos) is a synthetic 34-amino acid analogue of parathyroid hormone-relate…
Motixafortide
Motixafortide (Aphexda) is a cyclic peptide CXCR4 antagonist FDA-approved in 2023 in combi…
Palmitoyl Tripeptide-38
Palmitoyl tripeptide-38 (Matrixyl Synthe'6) is the primary active peptide of the Matrixyl …
Acetyl Tetrapeptide-5
Acetyl tetrapeptide-5 (Eyeseryl, Ac-beta-Ala-His-Ser-His) is a synthetic tetrapeptide cosm…
Parathyroid Hormone
Parathyroid hormone (PTH) is the principal regulator of extracellular calcium and phosphat…
Stanniocalcin
Stanniocalcin-1 (STC1) is a mammalian homolog of the fish corpuscles of Stannius hormone t…
Deltorphin
Deltorphins are a family of naturally occurring heptapeptides isolated from the skin of So…
Magainin
Magainins are cationic, alpha-helical antimicrobial peptides (AMPs) isolated from the skin…
Temporin
Temporins are a family of short (10-14 amino acid) cationic antimicrobial peptides isolate…
Dermaseptin
Dermaseptins are a family of 28-34 amino acid antimicrobial peptides first isolated from t…
Buforin II
Buforin II is a 21-residue antimicrobial peptide derived from histone H2A in the stomach o…
Brevinin
Brevinin peptides are a family of antimicrobial peptides isolated from the skin secretions…
Esculentin
Esculentins are the longest known naturally occurring antimicrobial peptides, isolated fro…
Aurein
Aurein peptides are a large family of short (13-25 residue) antimicrobial and anticancer p…
Caerin
Caerins are a family of antimicrobial peptides from the Australian Blue Mountains tree fro…
Tigerinin
Tigerinin peptides are isolated from the skin of the Indian skipper frog Hoplobatrachus ti…
PGLa
PGLa is a 22-residue alpha-helical antimicrobial peptide co-isolated with magainin-2 from …
Phylloseptin
Phylloseptins are a family of short, C-terminally amidated alpha-helical antimicrobial pep…
Maximin
Maximins are a large and diverse family of antimicrobial and neuroactive peptides isolated…
Chlorotoxin
Chlorotoxin is a 36-residue peptide toxin from the deathstalker scorpion (Leiurus quinques…
Lactoferricin
Lactoferricin B (LfcinB) is a 25-residue antimicrobial peptide released from the N-termina…
Leuphasyl
Leuphasyl (Acetyl Pentapeptide-18) is a synthetic cosmetic peptide designed to mimic enkep…
Syn-ake
Syn-ake is a synthetic tripeptide ingredient developed by DSM Nutritional Products that mi…
Rigin
Rigin (Palmitoyl Tetrapeptide-7) is a cosmetic peptide with the sequence Pal-GQPR derived …
Beta-Defensin 2
Human beta-defensin 2 (HBD-2) is an inducible antimicrobial peptide expressed by skin kera…
ALRN-6924
ALRN-6924 (sulanemadlin) is a hydrocarbon-stapled alpha-helical peptide developed by Ailer…
Dermcidin
Dermcidin is a constitutively expressed antimicrobial peptide produced by eccrine sweat gl…
Beta-Defensin-1
Human beta-defensin-1 (HBD-1) is a constitutively expressed antimicrobial peptide produced…
HNG
Humanin G (HNG) is a synthetic analog of the mitochondria-derived peptide humanin, in whic…
Litorin
Litorin is a bombesin-related nonapeptide isolated from the skin of Australian Litoria fro…
Ranatensin
Ranatensin is an 11-residue tachykinin peptide isolated from the skin of the North America…
PTHrP
Parathyroid hormone-related protein (PTHrP) is a polyhormone that shares N-terminal homolo…
Physalaemin
Physalaemin is an 11-residue tachykinin peptide first isolated from the skin of the South …
Kassinin
Kassinin is a tachykinin peptide isolated from the skin of the African frog Kassina senega…
Canstatin
Canstatin is the non-collagenous domain-1 (NC1) of the collagen IV alpha-2 chain, generate…
Endostatin
Endostatin is a 20 kDa C-terminal fragment of collagen XVIII generated by proteolytic clea…
Tumstatin
Tumstatin is the non-collagenous domain-1 (NC1) of the collagen IV alpha-3 chain (Col4a3),…
SDF-1 (CXCL12)
SDF-1 (CXCL12) is a constitutively expressed CXC chemokine produced by bone marrow stromal…
Lumican
Lumican is a keratan sulfate-bearing small leucine-rich proteoglycan (SLRP) critical for c…
Sclerostin
Sclerostin is a 190-amino-acid glycoprotein produced by osteocytes that acts as a potent i…
Dickkopf-1
Dickkopf-1 (DKK1) is a secreted Wnt signaling antagonist that binds the LRP5/LRP6 co-recep…
Osteocrin
Osteocrin (also called musclin) is a 103-amino-acid secreted peptide produced in bone (ost…
Galanin-Like Peptide
Galanin-like peptide (GALP) is a 60-amino-acid hypothalamic neuropeptide whose C-terminal …
Parathyroid Hormone 1-84
Parathyroid hormone 1-84 (PTH 1-84, Natpara) is the full-length recombinant human parathyr…
Palmitoyl Tripeptide-5
Palmitoyl tripeptide-5 (Pal-KVK) is a collagen-stimulating cosmetic peptide that mimics th…
Acetyl Tetrapeptide-9
Acetyl tetrapeptide-9 is a collagen-stimulating cosmetic peptide that specifically upregul…
Ventfort
Ventfort is a synthetic tripeptide (Lys-Glu-Asp) developed within the Khavinson bioregulat…
AHK-Cu
AHK-Cu is a copper-chelating tripeptide (Ala-His-Lys) that functions as a hair follicle st…
FOXO4-DRI
FOXO4-DRI is a D-retro-inverso peptide that selectively disrupts the interaction between F…
GHK
GHK (Glycyl-L-Histidyl-L-Lysine) is the copper-free form of the GHK-Cu tripeptide. While G…
Glow
Glow is a branded vendor blend combining GHK-Cu (copper tripeptide for skin regeneration),…
Glutathione
Glutathione (GSH) is the most abundant intracellular antioxidant in the human body, synthe…
NAD+
NAD+ (Nicotinamide Adenine Dinucleotide) is the oxidized form of the essential coenzyme NA…
Ovagen
Ovagen is a tripeptide bioregulator (Glu-Asp-Glu) developed by the St. Petersburg Institut…
Palmitoyl Pentapeptide-4
Palmitoyl Pentapeptide-4 (Pal-KTTKS, also marketed as Matrixyl) is a cosmetic peptide deri…
PNC-27
PNC-27 is a synthetic peptide containing the p53 HDM2-binding domain linked to a transmemb…
SNAP-8 / Argireline
SNAP-8 and Argireline are related cosmetic peptides that reduce wrinkle depth by partially…
Klotho
Klotho is an anti-aging protein encoded by the KL gene, named after the Greek Fate who spi…
Matrixyl
Matrixyl is the trade name for Palmitoyl Pentapeptide-4 (Pal-KTTKS), developed by Sederma …
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