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Hormonal & Reproductive

Fertility, reproductive, thyroid, pituitary, neuroendocrine

95 compounds
PT-141
PT-141 (Bremelanotide) is a cyclic heptapeptide analog of Melanotan II and alpha-MSH that …
Melanotan II
Melanotan II (MT-II) is a cyclic analog of alpha-melanocyte stimulating hormone (alpha-MSH…
Kisspeptin-10
Kisspeptin-10 is the minimal biologically active fragment of kisspeptin, the peptide prod…
Triptorelin
Triptorelin is a GnRH agonist with a D-tryptophan substitution at position 6, which confer…
Melanotan I
Melanotan I (afamelanotide) is a synthetic linear analog of alpha-melanocyte-stimulating h…
Alpha-MSH
Alpha-melanocyte stimulating hormone (alpha-MSH) is a 13-amino acid endogenous peptide cle…
ACTH 4-10
ACTH 4-10 is a heptapeptide corresponding to amino acids 4-10 of adrenocorticotropic hormo…
TRH
Thyrotropin-releasing hormone (TRH) is the smallest known hypothalamic regulatory peptide,…
Phoenixin
Phoenixin is a relatively newly discovered neuropeptide (2013) cleaved from the C-terminus…
Vasopressin
Arginine vasopressin (AVP), also called antidiuretic hormone (ADH), is a 9-amino acid cycl…
MCH
Melanin-concentrating hormone (MCH) is a 19-amino acid cyclic neuropeptide predominantly e…
CRH
Corticotropin-releasing hormone (CRH, also CRF) is a 41-amino acid hypothalamic peptide fi…
Neurokinin B
Neurokinin B (NKB) is a 10-amino acid tachykinin encoded by the TAC3 gene, preferentially …
Neuromedin S
Neuromedin S (NMS) is a 36-amino acid amidated neuropeptide discovered in 2005 that shares…
AgRP
Agouti-Related Protein (AgRP) is an endogenous neuropeptide produced by a small population…
Prokineticin-2
Prokineticin-2 (PROK2) is an 81-amino acid secreted signaling protein of the prokineticin …
Neuropeptide B
Neuropeptide B (NPB) is a 23-29 amino acid neuropeptide that, along with Neuropeptide W (N…
Neuropeptide W
Neuropeptide W (NPW) is a 23-30 amino acid peptide that, along with Neuropeptide B (NPB), …
Tetracosactide
Tetracosactide (cosyntropin, Synacthen) is a synthetic 24-amino acid analogue of the natur…
Desmopressin
Desmopressin (DDAVP) is a synthetic analogue of vasopressin (ADH) with two key modificatio…
Octreotide
Octreotide is a synthetic 8-amino acid cyclic peptide analogue of somatostatin with dramat…
ACTH
Adrenocorticotropic hormone (ACTH, corticotropin) is a 39-amino acid polypeptide produced …
Terlipressin
Terlipressin is a synthetic prodrug analogue of vasopressin (ADH), featuring a triglycine …
Leuprolide
Leuprolide acetate (leuprorelin) is a synthetic nonapeptide GnRH agonist that is approxima…
Carbetocin
Carbetocin is a synthetic long-acting analogue of oxytocin, approved in over 117 countries…
Afamelanotide
Afamelanotide is a synthetic 13-amino acid superagonist analogue of alpha-melanocyte-stimu…
Degarelix
Degarelix is a synthetic decapeptide GnRH antagonist that directly and competitively block…
Setmelanotide
Setmelanotide (Imcivree) is a cyclic octapeptide MC4R agonist FDA-approved in 2020 for chr…
Lanreotide
Lanreotide is a synthetic octapeptide somatostatin analog that preferentially binds somato…
Kisspeptin
Kisspeptin is the peptide product of the KISS1 gene, acting as the master regulator of the…
Gonadorelin
Gonadorelin is the synthetic form of native gonadotropin-releasing hormone (GnRH), also kn…
Cetrorelix
Cetrorelix is a synthetic GnRH receptor antagonist used in assisted reproductive technolog…
Atosiban
Atosiban is a competitive oxytocin and vasopressin V1a receptor antagonist developed speci…
Oxytocin
Oxytocin is a nine-amino acid neuropeptide and neurohormone synthesized in the hypothalami…
Parathyroid Hormone
Parathyroid hormone (PTH) is the principal regulator of extracellular calcium and phosphat…
Activin
Activin is a TGF-beta superfamily member functioning as a homodimer of inhibin-beta subuni…
Nesfatin-1
Nesfatin-1 is an 82-amino acid peptide derived from the N-terminal cleavage of nucleobindi…
Leptin Fragment (116-130)
Leptin fragment 116-130 is a 15-amino acid peptide derived from the active region of lepti…
Insulin-Like Peptide 3
Insulin-like peptide 3 (INSL3) is a member of the relaxin peptide family produced constitu…
Prolactin-Releasing Peptide
Prolactin-releasing peptide (PrRP) was originally identified as an endogenous ligand for t…
ACTH (Adrenocorticotropin)
Adrenocorticotropic hormone (ACTH) is a 39-amino acid peptide produced by the anterior pit…
CRH (Corticotropin-Releasing Hormone)
Corticotropin-releasing hormone (CRH, also called CRF) is the primary hypothalamic regulat…
TRH (Thyrotropin-Releasing Hormone)
Thyrotropin-releasing hormone (TRH) is the smallest known hypothalamic releasing hormone, …
Alpha-MSH
Alpha-melanocyte-stimulating hormone (alpha-MSH) is a 13-amino acid peptide derived from P…
Endokinin
Endokinins (EKA, EKB, EKC, EKD) are a family of tachykinin peptides encoded by the TAC4 ge…
GHRH
Growth hormone-releasing hormone (GHRH) is a 44-amino acid hypothalamic peptide that stimu…
Somatostatin
Somatostatin is a cyclic tetradecapeptide (SST-14) produced by hypothalamic neurons, pancr…
Melanotan I
Afamelanotide (Melanotan I, Scenesse) is an FDA-approved synthetic analog of alpha-melanoc…
Prokineticin-1
Prokineticin-1 (PROK1, also known as EG-VEGF for Endocrine Gland VEGF) is an 86-residue cy…
RFRP-3
RFamide-related peptide 3 (RFRP-3) is a mammalian neuropeptide that is the functional homo…
Neuropeptide VF
Neuropeptide VF (NPVF) is a member of the RF-amide neuropeptide family, characterized by a…
Kisspeptin-54
Kisspeptin-54 (KP-54, also called metastin) is the 54-amino acid full-length processed for…
Prodynorphin
Prodynorphin (PDYN) is the ~29 kDa opioid precursor polypeptide that is processed to yield…
Proopiomelanocortin
Proopiomelanocortin (POMC) is a 241-amino-acid prohormone that is the single precursor for…
Hemokinin-1
Hemokinin-1 (HK-1) is an 11-amino-acid tachykinin peptide encoded by the TAC4 gene, distin…
Canstatin
Canstatin is the non-collagenous domain-1 (NC1) of the collagen IV alpha-2 chain, generate…
Vasohibin-1
Vasohibin-1 (VASH1) is an endogenous angiogenesis inhibitor secreted by vascular endotheli…
Vasohibin-2
Vasohibin-2 (VASH2) is a paralog of vasohibin-1 with opposing function: it promotes angiog…
Endostatin
Endostatin is a 20 kDa C-terminal fragment of collagen XVIII generated by proteolytic clea…
Tumstatin
Tumstatin is the non-collagenous domain-1 (NC1) of the collagen IV alpha-3 chain (Col4a3),…
Angiostatin
Angiostatin is a proteolytic fragment of plasminogen comprising kringle domains 1 through …
Endothelin-3
Endothelin-3 (ET-3) is a 21-amino-acid vasoactive peptide from the endothelin family, gene…
Big Endothelin-1
Big endothelin-1 (Big ET-1) is the 38-amino-acid immediate precursor of endothelin-1, gene…
Salusin-Alpha
Salusin-alpha is a 28-amino-acid peptide derived from prosalusin, an endogenous precursor …
Phoenixin-14
Phoenixin-14 is a novel amidated neuropeptide discovered in 2013 through bioinformatics an…
Secretoneurin
Secretoneurin is a 33-amino acid neuropeptide derived from secretogranin II (chromogranin …
Leu-Enkephalin
Leucine enkephalin (Leu-enkephalin) is a five-amino-acid endogenous opioid pentapeptide (T…
Met-Enkephalin
Methionine enkephalin (Met-enkephalin) is the five-amino-acid endogenous opioid pentapepti…
Thymosin Alpha 5
Thymosin alpha 5 (Ta5) is an acidic polypeptide thymic hormone fragment isolated from calf…
Proenkephalin
Proenkephalin (PENK or Proenkephalin A) is the 267-amino-acid precursor polypeptide that y…
GDF-9
Growth differentiation factor 9 (GDF-9) is a TGF-beta superfamily member produced exclusiv…
Osteocrin
Osteocrin (also called musclin) is a 103-amino-acid secreted peptide produced in bone (ost…
PAMP
PAMP (proadrenomedullin N-terminal 20 peptide) is a 20-amino-acid peptide derived from the…
Relaxin-1
Relaxin-1 (RLN1) is the first member of the relaxin peptide family discovered, originally …
Trefoil Factor 1
Trefoil factor 1 (TFF1) is a 6.6 kDa secreted peptide produced predominantly by gastric pi…
Trefoil Factor 3
Trefoil factor 3 (TFF3), also called intestinal trefoil factor (ITF), is the most abundant…
Galanin-Like Peptide
Galanin-like peptide (GALP) is a 60-amino-acid hypothalamic neuropeptide whose C-terminal …
QRFP (26RFa)
QRFP (also called 26RFa) is a C-terminally amidated RFamide neuropeptide first identified …
Dynorphin B
Dynorphin B (also called rimorphin) is a 13-amino-acid kappa-opioid receptor agonist deriv…
Parathyroid Hormone 1-84
Parathyroid hormone 1-84 (PTH 1-84, Natpara) is the full-length recombinant human parathyr…
Inhibin A
Inhibin A is a dimeric glycoprotein (alpha/beta-A subunit) of the TGF-beta superfamily pro…
Inhibin B
Inhibin B is the alpha/beta-B dimeric form of inhibin, the dominant FSH-suppressing hormon…
Nafarelin
Nafarelin is a synthetic GnRH agonist 200x more potent than native GnRH, administered intr…
Histrelin
Histrelin is a potent synthetic GnRH superagonist delivered via a once-yearly subcutaneous…
Buserelin
Buserelin is a synthetic GnRH agonist approximately 100x more potent than native GnRH, ava…
Deslorelin
Deslorelin is a synthetic GnRH superagonist primarily used in veterinary medicine (Suprelo…
Felypressin
Felypressin is a synthetic vasopressin analog used exclusively in dental local anesthetic …
Anti-Mullerian Hormone
Anti-Mullerian hormone (AMH) is a dimeric glycoprotein member of the TGF-beta superfamily …
Alamandine
Alamandine is a recently discovered heptapeptide of the renin-angiotensin system (RAS) for…
Angiotensin IV
Angiotensin IV (Ang IV) is the hexapeptide fragment of the renin-angiotensin system formed…
HCG
Human Chorionic Gonadotropin (hCG) is a glycoprotein hormone naturally produced by the pla…
HMG
Human Menopausal Gonadotropin (hMG) is a purified preparation of FSH (follicle-stimulating…
Melanotan II
Melanotan II (MT-II) is a synthetic analog of alpha-MSH (alpha-melanocyte-stimulating horm…
Prostamax
Prostamax is a tetrapeptide bioregulator (Ala-Glu-Asp-Gly) developed by the Khavinson Inst…
Testagen
Testagen is a tripeptide bioregulator (Lys-Asp-Glu) from the Khavinson Institute, targeted…
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