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Hormonal & Reproductive

Fertility, reproductive, thyroid, pituitary, neuroendocrine

95 compounds
PT-141
PT-141 (Bremelanotide) is a cyclic heptapeptide analog of Melanotan II and alpha-MSH that …
Melanotan II
Melanotan II (MT-II) is a cyclic analog of alpha-melanocyte stimulating hormone (alpha-MSH…
Kisspeptin-10
Kisspeptin-10 is the minimal biologically active fragment of kisspeptin, the peptide prod…
Oxytocin
Oxytocin is a nine-amino acid neuropeptide and neurohormone synthesized in the hypothalami…
Gonadorelin
Gonadorelin is the synthetic form of native gonadotropin-releasing hormone (GnRH), also kn…
Triptorelin
Triptorelin is a GnRH agonist with a D-tryptophan substitution at position 6, which confer…
Melanotan I
Melanotan I (afamelanotide) is a synthetic linear analog of alpha-melanocyte-stimulating h…
Nesfatin-1
Nesfatin-1 is an 82-amino acid peptide derived from the N-terminal cleavage of nucleobindi…
Somatostatin
Somatostatin is a cyclic tetradecapeptide (SST-14) produced by hypothalamic neurons, pancr…
Alpha-MSH
Alpha-melanocyte stimulating hormone (alpha-MSH) is a 13-amino acid endogenous peptide cle…
ACTH 4-10
ACTH 4-10 is a heptapeptide corresponding to amino acids 4-10 of adrenocorticotropic hormo…
TRH
Thyrotropin-releasing hormone (TRH) is the smallest known hypothalamic regulatory peptide,…
Phoenixin
Phoenixin is a relatively newly discovered neuropeptide (2013) cleaved from the C-terminus…
Vasopressin
Arginine vasopressin (AVP), also called antidiuretic hormone (ADH), is a 9-amino acid cycl…
MCH
Melanin-concentrating hormone (MCH) is a 19-amino acid cyclic neuropeptide predominantly e…
CRH
Corticotropin-releasing hormone (CRH, also CRF) is a 41-amino acid hypothalamic peptide fi…
Neurokinin B
Neurokinin B (NKB) is a 10-amino acid tachykinin encoded by the TAC3 gene, preferentially …
Neuromedin S
Neuromedin S (NMS) is a 36-amino acid amidated neuropeptide discovered in 2005 that shares…
AgRP
Agouti-Related Protein (AgRP) is an endogenous neuropeptide produced by a small population…
Prokineticin-2
Prokineticin-2 (PROK2) is an 81-amino acid secreted signaling protein of the prokineticin …
Neuropeptide B
Neuropeptide B (NPB) is a 23-29 amino acid neuropeptide that, along with Neuropeptide W (N…
Neuropeptide W
Neuropeptide W (NPW) is a 23-30 amino acid peptide that, along with Neuropeptide B (NPB), …
Tetracosactide
Tetracosactide (cosyntropin, Synacthen) is a synthetic 24-amino acid analogue of the natur…
Desmopressin
Desmopressin (DDAVP) is a synthetic analogue of vasopressin (ADH) with two key modificatio…
Octreotide
Octreotide is a synthetic 8-amino acid cyclic peptide analogue of somatostatin with dramat…
ACTH
Adrenocorticotropic hormone (ACTH, corticotropin) is a 39-amino acid polypeptide produced …
Terlipressin
Terlipressin is a synthetic prodrug analogue of vasopressin (ADH), featuring a triglycine …
Leuprolide
Leuprolide acetate (leuprorelin) is a synthetic nonapeptide GnRH agonist that is approxima…
Carbetocin
Carbetocin is a synthetic long-acting analogue of oxytocin, approved in over 117 countries…
Afamelanotide
Afamelanotide is a synthetic 13-amino acid superagonist analogue of alpha-melanocyte-stimu…
Degarelix
Degarelix is a synthetic decapeptide GnRH antagonist that directly and competitively block…
Setmelanotide
Setmelanotide (Imcivree) is a cyclic octapeptide MC4R agonist FDA-approved in 2020 for chr…
Lanreotide
Lanreotide is a synthetic octapeptide somatostatin analog that preferentially binds somato…
Kisspeptin
Kisspeptin is the peptide product of the KISS1 gene, acting as the master regulator of the…
Cetrorelix
Cetrorelix is a synthetic GnRH receptor antagonist used in assisted reproductive technolog…
Atosiban
Atosiban is a competitive oxytocin and vasopressin V1a receptor antagonist developed speci…
Parathyroid Hormone
Parathyroid hormone (PTH) is the principal regulator of extracellular calcium and phosphat…
Activin
Activin is a TGF-beta superfamily member functioning as a homodimer of inhibin-beta subuni…
Leptin Fragment (116-130)
Leptin fragment 116-130 is a 15-amino acid peptide derived from the active region of lepti…
Insulin-Like Peptide 3
Insulin-like peptide 3 (INSL3) is a member of the relaxin peptide family produced constitu…
Prolactin-Releasing Peptide
Prolactin-releasing peptide (PrRP) was originally identified as an endogenous ligand for t…
ACTH (Adrenocorticotropin)
Adrenocorticotropic hormone (ACTH) is a 39-amino acid peptide produced by the anterior pit…
CRH (Corticotropin-Releasing Hormone)
Corticotropin-releasing hormone (CRH, also called CRF) is the primary hypothalamic regulat…
TRH (Thyrotropin-Releasing Hormone)
Thyrotropin-releasing hormone (TRH) is the smallest known hypothalamic releasing hormone, …
Alpha-MSH
Alpha-melanocyte-stimulating hormone (alpha-MSH) is a 13-amino acid peptide derived from P…
Endokinin
Endokinins (EKA, EKB, EKC, EKD) are a family of tachykinin peptides encoded by the TAC4 ge…
GHRH
Growth hormone-releasing hormone (GHRH) is a 44-amino acid hypothalamic peptide that stimu…
Melanotan I
Afamelanotide (Melanotan I, Scenesse) is an FDA-approved synthetic analog of alpha-melanoc…
Prokineticin-1
Prokineticin-1 (PROK1, also known as EG-VEGF for Endocrine Gland VEGF) is an 86-residue cy…
RFRP-3
RFamide-related peptide 3 (RFRP-3) is a mammalian neuropeptide that is the functional homo…
Neuropeptide VF
Neuropeptide VF (NPVF) is a member of the RF-amide neuropeptide family, characterized by a…
Kisspeptin-54
Kisspeptin-54 (KP-54, also called metastin) is the 54-amino acid full-length processed for…
Prodynorphin
Prodynorphin (PDYN) is the ~29 kDa opioid precursor polypeptide that is processed to yield…
Proopiomelanocortin
Proopiomelanocortin (POMC) is a 241-amino-acid prohormone that is the single precursor for…
Hemokinin-1
Hemokinin-1 (HK-1) is an 11-amino-acid tachykinin peptide encoded by the TAC4 gene, distin…
Canstatin
Canstatin is the non-collagenous domain-1 (NC1) of the collagen IV alpha-2 chain, generate…
Vasohibin-1
Vasohibin-1 (VASH1) is an endogenous angiogenesis inhibitor secreted by vascular endotheli…
Vasohibin-2
Vasohibin-2 (VASH2) is a paralog of vasohibin-1 with opposing function: it promotes angiog…
Endostatin
Endostatin is a 20 kDa C-terminal fragment of collagen XVIII generated by proteolytic clea…
Tumstatin
Tumstatin is the non-collagenous domain-1 (NC1) of the collagen IV alpha-3 chain (Col4a3),…
Angiostatin
Angiostatin is a proteolytic fragment of plasminogen comprising kringle domains 1 through …
Endothelin-3
Endothelin-3 (ET-3) is a 21-amino-acid vasoactive peptide from the endothelin family, gene…
Big Endothelin-1
Big endothelin-1 (Big ET-1) is the 38-amino-acid immediate precursor of endothelin-1, gene…
Salusin-Alpha
Salusin-alpha is a 28-amino-acid peptide derived from prosalusin, an endogenous precursor …
Phoenixin-14
Phoenixin-14 is a novel amidated neuropeptide discovered in 2013 through bioinformatics an…
Secretoneurin
Secretoneurin is a 33-amino acid neuropeptide derived from secretogranin II (chromogranin …
Leu-Enkephalin
Leucine enkephalin (Leu-enkephalin) is a five-amino-acid endogenous opioid pentapeptide (T…
Met-Enkephalin
Methionine enkephalin (Met-enkephalin) is the five-amino-acid endogenous opioid pentapepti…
Thymosin Alpha 5
Thymosin alpha 5 (Ta5) is an acidic polypeptide thymic hormone fragment isolated from calf…
Proenkephalin
Proenkephalin (PENK or Proenkephalin A) is the 267-amino-acid precursor polypeptide that y…
GDF-9
Growth differentiation factor 9 (GDF-9) is a TGF-beta superfamily member produced exclusiv…
Osteocrin
Osteocrin (also called musclin) is a 103-amino-acid secreted peptide produced in bone (ost…
PAMP
PAMP (proadrenomedullin N-terminal 20 peptide) is a 20-amino-acid peptide derived from the…
Relaxin-1
Relaxin-1 (RLN1) is the first member of the relaxin peptide family discovered, originally …
Trefoil Factor 1
Trefoil factor 1 (TFF1) is a 6.6 kDa secreted peptide produced predominantly by gastric pi…
Trefoil Factor 3
Trefoil factor 3 (TFF3), also called intestinal trefoil factor (ITF), is the most abundant…
Galanin-Like Peptide
Galanin-like peptide (GALP) is a 60-amino-acid hypothalamic neuropeptide whose C-terminal …
QRFP (26RFa)
QRFP (also called 26RFa) is a C-terminally amidated RFamide neuropeptide first identified …
Dynorphin B
Dynorphin B (also called rimorphin) is a 13-amino-acid kappa-opioid receptor agonist deriv…
Parathyroid Hormone 1-84
Parathyroid hormone 1-84 (PTH 1-84, Natpara) is the full-length recombinant human parathyr…
Inhibin A
Inhibin A is a dimeric glycoprotein (alpha/beta-A subunit) of the TGF-beta superfamily pro…
Inhibin B
Inhibin B is the alpha/beta-B dimeric form of inhibin, the dominant FSH-suppressing hormon…
Nafarelin
Nafarelin is a synthetic GnRH agonist 200x more potent than native GnRH, administered intr…
Histrelin
Histrelin is a potent synthetic GnRH superagonist delivered via a once-yearly subcutaneous…
Buserelin
Buserelin is a synthetic GnRH agonist approximately 100x more potent than native GnRH, ava…
Deslorelin
Deslorelin is a synthetic GnRH superagonist primarily used in veterinary medicine (Suprelo…
Felypressin
Felypressin is a synthetic vasopressin analog used exclusively in dental local anesthetic …
Anti-Mullerian Hormone
Anti-Mullerian hormone (AMH) is a dimeric glycoprotein member of the TGF-beta superfamily …
Alamandine
Alamandine is a recently discovered heptapeptide of the renin-angiotensin system (RAS) for…
Angiotensin IV
Angiotensin IV (Ang IV) is the hexapeptide fragment of the renin-angiotensin system formed…
HCG
Human Chorionic Gonadotropin (hCG) is a glycoprotein hormone naturally produced by the pla…
HMG
Human Menopausal Gonadotropin (hMG) is a purified preparation of FSH (follicle-stimulating…
Melanotan II
Melanotan II (MT-II) is a synthetic analog of alpha-MSH (alpha-melanocyte-stimulating horm…
Prostamax
Prostamax is a tetrapeptide bioregulator (Ala-Glu-Asp-Gly) developed by the Khavinson Inst…
Testagen
Testagen is a tripeptide bioregulator (Lys-Asp-Glu) from the Khavinson Institute, targeted…
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