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Weight Loss & Metabolic
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Weight Loss & Metabolic
GLP-1 agonists, metabolic, satiety peptides
77 compounds
L-Carnitine
L-Carnitine (Levocarnitine) is a naturally occurring quaternary ammonium compound synthesi…
Methylcobalamin
Methylcobalamin is the biologically active, methyl-group-carrying form of Vitamin B12 (cob…
Lipo-C
Lipo-C (Lipotropic Compound) is a pre-mixed injectable blend containing lipotropic agents …
Semaglutide
Semaglutide is a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist developed by…
AOD-9604
AOD-9604 is a synthetic peptide corresponding to the C-terminal fragment of human growth h…
Tesamorelin
Tesamorelin (Egrifta) is a GHRH analog modified with a trans-3-hexenoic acid group at the …
Tirzepatide
Tirzepatide is a first-in-class dual glucose-dependent insulinotropic polypeptide (GIP) an…
Retatrutide
Retatrutide is a first-in-class triple receptor agonist developed by Eli Lilly that simult…
Cagrilintide
Cagrilintide is a long-acting amylin analog developed by Novo Nordisk that acts on amylin …
AICAR
AICAR (Acadesine) is a cell-permeable adenosine analog that is phosphorylated intracellula…
Liraglutide
Liraglutide is a once-daily GLP-1 receptor agonist developed by Novo Nordisk that was the …
Pemvidutide
Pemvidutide (ALT-801) is a GLP-1 and glucagon receptor dual agonist developed by Altimmune…
Exendin-4
Exendin-4 is a 39-amino acid peptide isolated from the venom of the Gila monster lizard (H…
SLU-PP-332
SLU-PP-332 is a synthetic pan-agonist of the estrogen-related receptor (ERR) subfamily, E…
Neuropeptide Y
Neuropeptide Y (NPY) is one of the most abundantly expressed neuropeptides in the mammalia…
Ghrelin
Ghrelin is a 28-amino acid orexigenic peptide primarily secreted by X/A-like enteroendocri…
Angiotensin (1-7)
Angiotensin (1-7) is a heptapeptide member of the renin-angiotensin system (RAS) that acts…
Nesfatin-1
Nesfatin-1 is an 82-amino acid peptide derived from the N-terminal cleavage of nucleobindi…
Amylin
Amylin (islet amyloid polypeptide, IAPP) is a 37-amino acid peptide co-secreted with insul…
GIP
Glucose-dependent insulinotropic peptide (GIP) is a 42-amino-acid incretin hormone secrete…
Peptide YY
Peptide YY (PYY) is a 36-amino acid NPY-family peptide released from enteroendocrine L cel…
Leptin
Leptin is a 167-amino-acid adipokine hormone produced by adipocytes in proportion to body …
Oxyntomodulin
Oxyntomodulin (OXM) is a 37-amino-acid peptide derived from the proglucagon gene in intest…
Apelin-13
Apelin-13 is the most biologically active isoform of the apelin peptide family, endogenous…
Irisin
Irisin is a hormone-like myokine released from skeletal muscle during exercise, generated …
FGF-21
Fibroblast Growth Factor 21 (FGF-21) is an endocrine member of the FGF superfamily that fu…
Bombesin
Bombesin is a 14-amino acid neuropeptide originally isolated from the skin of the European…
CCK
Cholecystokinin (CCK) is a peptide hormone and neuropeptide produced in the intestinal I-c…
Glucagon
Glucagon is a 29-amino acid peptide hormone secreted by pancreatic alpha cells in response…
Neuromedin U
Neuromedin U (NMU) is a neuropeptide first isolated from porcine spinal cord and named for…
Spexin
Spexin is a 14-amino acid amidated neuropeptide encoded by the C12orf39 gene, identified t…
MCH
Melanin-concentrating hormone (MCH) is a 19-amino acid cyclic neuropeptide predominantly e…
CART Peptide
CART (Cocaine- and Amphetamine-Regulated Transcript) peptide is a neuropeptide encoded by …
Obestatin
Obestatin is a 23-amino acid amidated peptide derived from the same preproghrelin precurso…
Insulin
Insulin is a 51-amino acid two-chain peptide hormone secreted by pancreatic beta cells in …
GLP-1
Glucagon-like peptide-1 (GLP-1 7-36 amide) is a 30-amino acid incretin hormone secreted po…
Xenin-25
Xenin-25 is a 25-amino acid peptide co-secreted with GIP (glucose-dependent insulinotropic…
Neuromedin S
Neuromedin S (NMS) is a 36-amino acid amidated neuropeptide discovered in 2005 that shares…
Hemopressin
Hemopressin is a 9-amino acid peptide derived from the alpha-chain of hemoglobin (residues…
AgRP
Agouti-Related Protein (AgRP) is an endogenous neuropeptide produced by a small population…
Asprosin
Asprosin is a 30 kDa protein hormone discovered in 2016 as the C-terminal cleavage product…
Adropin
Adropin is a secreted peptide encoded by the Energy Homeostasis-Associated (ENHO) gene, ex…
Neuropeptide B
Neuropeptide B (NPB) is a 23-29 amino acid neuropeptide that, along with Neuropeptide W (N…
Neuropeptide W
Neuropeptide W (NPW) is a 23-30 amino acid peptide that, along with Neuropeptide B (NPB), …
LEAP-2
LEAP-2 (Liver-Expressed Antimicrobial Peptide 2) was originally identified as a hepatic an…
Osteocalcin
Osteocalcin is a 49-amino acid protein produced by osteoblasts and odontoblasts that was l…
Preptin
Preptin is a 34-amino acid peptide co-secreted with insulin and amylin from pancreatic bet…
FGF-19
FGF-19 is a 216-amino acid endocrine member of the fibroblast growth factor superfamily, s…
Meteorin-Like
Meteorin-Like (METRNL) is a secreted glycoprotein produced by skeletal muscle during exerc…
Pramlintide
Pramlintide is a synthetic analogue of human amylin, a 37-amino acid peptide co-secreted w…
Cerulein
Cerulein (caerulein) is a 10-amino acid peptide originally isolated from the skin of the A…
Setmelanotide
Setmelanotide (Imcivree) is a cyclic octapeptide MC4R agonist FDA-approved in 2020 for chr…
Cholecystokinin
Cholecystokinin (CCK) is a peptide hormone secreted by enteroendocrine I-cells of the smal…
Pancreatic Polypeptide
Pancreatic polypeptide (PP) is a 36-amino acid member of the NPY/PYY peptide family secret…
Uroguanylin
Uroguanylin is a 16-amino acid peptide hormone secreted by enterochromaffin cells of the p…
FGF-21
FGF-21 is an atypical member of the fibroblast growth factor family that lacks heparan sul…
Leptin Fragment (116-130)
Leptin fragment 116-130 is a 15-amino acid peptide derived from the active region of lepti…
Prolactin-Releasing Peptide
Prolactin-releasing peptide (PrRP) was originally identified as an endogenous ligand for t…
GIP
Glucose-dependent insulinotropic peptide (GIP) is a 42-amino acid incretin hormone secrete…
Survodutide
Survodutide (BI 456906) is a dual agonist of GLP-1 receptors (GLP-1R) and glucagon recepto…
Efinopegdutide
Efinopegdutide (MK-6024, HM12525A) is a PEGylated dual GLP-1R/glucagon receptor agonist de…
Avexitide
Avexitide (exendin 9-39) is a competitive antagonist of the GLP-1 receptor derived from a …
IAPP
Islet amyloid polypeptide (IAPP), also called amylin, is a 37-amino acid peptide co-secret…
PYY3-36
PYY3-36 is the predominant bioactive circulating form of peptide YY (PYY), produced by dip…
MCH
Melanin-concentrating hormone (MCH) is a cyclic 19-amino acid neuropeptide expressed by ne…
Somatostatin-28
Somatostatin-28 (SS-28) is the 28-amino acid form of somatostatin produced primarily by in…
Des-Acyl Ghrelin
Des-acyl ghrelin (UAG) is the predominant circulating form of ghrelin, comprising ~80-90% …
Neuromedin C
Neuromedin C (NMC) is the C-terminal decapeptide (aa18-27) of gastrin-releasing peptide (G…
QRFP (26RFa)
QRFP (also called 26RFa) is a C-terminally amidated RFamide neuropeptide first identified …
GDF-15
GDF-15 is a stress-responsive member of the TGF-beta superfamily that acts as the primary …
Cotadutide
Cotadutide (MEDI0382) is a once-daily subcutaneous dual agonist of GLP-1 and glucagon rece…
5-Amino-1MQ
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), an e…
Adipotide
Adipotide (FTPP) is an experimental peptidomimetic that selectively targets and destroys b…
AOD-9604
AOD-9604 (Anti-Obesity Drug 9604) is a synthetic fragment of human growth hormone (hGH), s…
CagriSema
CagriSema is the research name for the combination of cagrilintide (an amylin analog) and …
Dulaglutide
Dulaglutide (Trulicity) is a once-weekly GLP-1 receptor agonist approved by the FDA for th…
Mazdutide
Mazdutide (IBI362) is a once-weekly GLP-1/glucagon receptor dual agonist developed by Inno…
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