TESTOSTERONE ESTER COMPARISON

Testosterone Ester Dose SchedulesCypionate · Enanthate · Propionate · Undecanoate · Topical · Pellet

Side-by-side schedule and half-life comparison for the testosterone formulations used in clinical TRT and research. Use the linked calculators for vial-specific draw volumes.

Depo-Testosterone

Active
Testosterone Cypionate
Half-life
~8 days (mean)
Schedule
Typical clinical dosing: 50 to 200 mg IM every 7 to 14 days; some protocols split to twice-weekly subcutaneous administration for steadier levels.
Depo-Testosterone full reference →

Delatestryl

Active
Testosterone Enanthate
Half-life
~7 days (mean)
Schedule
Typical clinical dosing: 50 to 200 mg IM every 7 to 14 days. Pharmacokinetics overlap closely with cypionate.
Delatestryl full reference →

Aveed

Active
Testosterone Undecanoate
Half-life
~33 days
Schedule
Loading: 750 mg IM at week 0 and week 4. Maintenance: 750 mg IM every 10 weeks thereafter.
Aveed full reference →

Xyosted

Active
Testosterone Enanthate (subcutaneous auto-injector)
Half-life
~7 days
Schedule
Once weekly subcutaneous injection. Start dose 75 mg/week; adjust based on serum total testosterone after 6 weeks.
Xyosted full reference →

AndroGel

Active
Testosterone (transdermal gel)
Half-life
N/A (continuous transdermal absorption)
Schedule
Once daily topical application to shoulders, upper arms, or abdomen. Allow to dry; wash hands; avoid skin-to-skin contact with women and children for several hours.
AndroGel full reference →

Testopel

Active
Testosterone (subcutaneous pellet)
Half-life
Continuous release over 3 to 6 months
Schedule
In-office trochar insertion into the subcutaneous fat of the hip or buttock under local anesthetic. Re-implant every 3 to 6 months.
Testopel full reference →

Compound Testosterone Cypionate

Active
Testosterone Cypionate
Half-life
~8 days
Schedule
Same as Depo-Testosterone (50 to 200 mg every 7 to 14 days IM or SC). Cost is meaningfully lower than the branded product.
Compound Testosterone Cypionate full reference →

Compound Testosterone Enanthate

Active
Testosterone Enanthate
Half-life
~7 days
Schedule
Functionally equivalent to compound cypionate for clinical dosing purposes.
Compound Testosterone Enanthate full reference →

Compound Testosterone Propionate

Active
Testosterone Propionate
Half-life
~0.8 days (very short)
Schedule
Every-other-day IM or SC injection. Rarely used for routine TRT; sometimes selected for short-duration research protocols where rapid titration up or down is desired.
Compound Testosterone Propionate full reference →

For research informational use only. Not medical advice. Testosterone esters are Schedule III controlled substances in the United States.

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