FDA-APPROVED
TestopelActive: Testosterone (subcutaneous pellet)
Quick reference: In-office trochar insertion into the subcutaneous fat of the hip or buttock under local anesthetic. Re-implant every 3 to 6 months.
Fast facts
Active
Testosterone (subcutaneous pellet)
Maker
Endo Pharmaceuticals
FDA Approval
1972
Half-life
Continuous release over 3 to 6 months
Form
75 mg cylindrical fused crystalline pellets. Typical implant: 6 to 12 pellets (450 to 900 mg) every 3 to 6 months.
Indication
FDA-approved long-acting subcutaneous testosterone pellet for hypogonadism in adult males
Dose schedule
In-office trochar insertion into the subcutaneous fat of the hip or buttock under local anesthetic. Re-implant every 3 to 6 months.
Recommended monitoring
Trough TT at 2 to 3 months; adjust pellet count at next implant.
Clinical notes
Set-and-forget dosing schedule. Pellet extrusion (rare), infection, and inability to titrate mid-cycle are the practical downsides.
Controlled substance. Testosterone esters are Schedule III in the United States. A valid prescription from a DEA-registered prescriber is required. This page is research informational reference only.
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Frequently asked
What is the typical dose schedule for Testopel?
In-office trochar insertion into the subcutaneous fat of the hip or buttock under local anesthetic. Re-implant every 3 to 6 months.
What is the half-life of Testosterone (subcutaneous pellet)?
Testopel has a half-life of approximately Continuous release over 3 to 6 months.
What monitoring labs are recommended on Testopel?
Trough TT at 2 to 3 months; adjust pellet count at next implant.
Is Testopel the same as compounded testosterone (subcutaneous pellet)?
Testopel is a finished FDA-approved drug product with consistent quality control. Compounded testosterone (subcutaneous pellet) produced by 503A or 503B pharmacies contains the same active ester but is not held to identical manufacturing standards. Verify the Certificate of Analysis when using a compound.
Is Testopel a controlled substance?
Yes. Testosterone and its esters are Schedule III controlled substances in the United States. A valid prescription from a DEA-registered prescriber is required to obtain Testopel legally. State-level regulations may impose additional restrictions.
Related
For research informational use only. Not medical advice. Testopel is a registered trademark of Endo Pharmaceuticals. Consult a qualified healthcare provider before any clinical decision. ASCEND, ascendpeptide.org