FDA-APPROVED
XyostedActive: Testosterone Enanthate (subcutaneous auto-injector)
Quick reference: Once weekly subcutaneous injection. Start dose 75 mg/week; adjust based on serum total testosterone after 6 weeks.
Fast facts
Active
Testosterone Enanthate (subcutaneous auto-injector)
Maker
Antares Pharma (now Halozyme)
FDA Approval
2018
Half-life
~7 days
Form
Single-use subcutaneous auto-injector, 50 / 75 / 100 mg per pen.
Indication
FDA-approved for replacement therapy in conditions associated with deficiency or absence of endogenous testosterone in adult males
Dose schedule
Once weekly subcutaneous injection. Start dose 75 mg/week; adjust based on serum total testosterone after 6 weeks.
Recommended monitoring
Trough TT after 6 weeks of stable dosing; sensitive E2 if symptoms warrant; hematocrit at baseline and 3 to 6 months.
Clinical notes
First and only FDA-approved subcutaneous auto-injector form. Designed for steadier weekly levels than every-two-week IM cypionate.
Controlled substance. Testosterone esters are Schedule III in the United States. A valid prescription from a DEA-registered prescriber is required. This page is research informational reference only.
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Frequently asked
What is the typical dose schedule for Xyosted?
Once weekly subcutaneous injection. Start dose 75 mg/week; adjust based on serum total testosterone after 6 weeks.
What is the half-life of Testosterone Enanthate (subcutaneous auto-injector)?
Xyosted has a half-life of approximately ~7 days. Steady-state plasma levels are reached after roughly four to six half-lives of consistent dosing.
What monitoring labs are recommended on Xyosted?
Trough TT after 6 weeks of stable dosing; sensitive E2 if symptoms warrant; hematocrit at baseline and 3 to 6 months.
Is Xyosted the same as compounded testosterone enanthate (subcutaneous auto-injector)?
Xyosted is a finished FDA-approved drug product with consistent quality control. Compounded testosterone enanthate (subcutaneous auto-injector) produced by 503A or 503B pharmacies contains the same active ester but is not held to identical manufacturing standards. Verify the Certificate of Analysis when using a compound.
Is Xyosted a controlled substance?
Yes. Testosterone and its esters are Schedule III controlled substances in the United States. A valid prescription from a DEA-registered prescriber is required to obtain Xyosted legally. State-level regulations may impose additional restrictions.
Related
For research informational use only. Not medical advice. Xyosted is a registered trademark of Antares Pharma (now Halozyme). Consult a qualified healthcare provider before any clinical decision. ASCEND, ascendpeptide.org