Quick reference: Typical clinical dosing: 50 to 200 mg IM every 7 to 14 days; some protocols split to twice-weekly subcutaneous administration for steadier levels.
Fast facts
Active
Testosterone Cypionate
Maker
Pfizer (originator) and multiple generics
FDA Approval
1979
Half-life
~8 days (mean)
Form
Intramuscular injection, oil vehicle. Common strengths: 100 mg/mL and 200 mg/mL multidose vials.
Indication
FDA-approved treatment of primary or hypogonadotropic hypogonadism in adult males with documented low total testosterone and symptoms consistent with androgen deficiency
Dose schedule
Typical clinical dosing: 50 to 200 mg IM every 7 to 14 days; some protocols split to twice-weekly subcutaneous administration for steadier levels.
Recommended monitoring
Trough total testosterone, estradiol (sensitive assay), hematocrit, PSA in age-appropriate cohorts.
Clinical notes
The most prescribed testosterone ester in the US. Steady-state achieved after 4 to 6 half-lives (~32 to 48 days).
Controlled substance. Testosterone esters are Schedule III in the United States. A valid prescription from a DEA-registered prescriber is required. This page is research informational reference only.
What is the typical dose schedule for Depo-Testosterone?
Typical clinical dosing: 50 to 200 mg IM every 7 to 14 days; some protocols split to twice-weekly subcutaneous administration for steadier levels.
What is the half-life of Testosterone Cypionate?
Depo-Testosterone has a half-life of approximately ~8 days (mean). Steady-state plasma levels are reached after roughly four to six half-lives of consistent dosing.
What monitoring labs are recommended on Depo-Testosterone?
Trough total testosterone, estradiol (sensitive assay), hematocrit, PSA in age-appropriate cohorts.
Is Depo-Testosterone the same as compounded testosterone cypionate?
Depo-Testosterone is a finished FDA-approved drug product with consistent quality control. Compounded testosterone cypionate produced by 503A or 503B pharmacies contains the same active ester but is not held to identical manufacturing standards. Verify the Certificate of Analysis when using a compound.
Is Depo-Testosterone a controlled substance?
Yes. Testosterone and its esters are Schedule III controlled substances in the United States. A valid prescription from a DEA-registered prescriber is required to obtain Depo-Testosterone legally. State-level regulations may impose additional restrictions.
For research informational use only. Not medical advice. Depo-Testosterone is a registered trademark of Pfizer (originator) and multiple generics. Consult a qualified healthcare provider before any clinical decision. ASCEND, ascendpeptide.org