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Synapsin

⊘ Vendor / Research
Synapsin, GHK-Cu + Dihexa Nootropic Blend (Intranasal)
Also known as: Synapsin blend, GHK-Cu Dihexa intranasal, synaptic density blend
Brand names: Synapsin (vendor blend)
Page last reviewed

Quick Summary

Synapsin is a proprietary intranasal peptide blend combining GHK-Cu (copper tripeptide for neuroregenerative and anti-inflammatory effects) and Dihexa (a potent HGF/c-Met agonist for synaptogenesis and memory). The combination targets synaptic density and cognitive performance from two mechanistically distinct angles: GHK-Cu via its broad gene-regulatory and neurotrophic effects, and Dihexa via direct HGF pathway activation in the CNS.

Cognitive & Neurological Vendor Blend
Synapsin is a proprietary intranasal peptide blend combining GHK-Cu (copper tripeptide for neuroregenerative and anti-inflammatory effects) and Dihexa (a potent HGF/c-Met agonist for synaptogenesis and memory). The combination targets synaptic density and cognitive performance from two mechanistically distinct angles: GHK-Cu via its broad gene-regulatory and neurotrophic effects, and Dihexa via direct HGF pathway activation in the CNS.
Storage Stability
Lyophilized
6–12 months (2–8°C)
Reconstituted
~30 days (2–8°C)
Room temp
Avoid

Mechanism of Action

GHK-Cu Component

GHK-Cu in the CNS context modulates expression of anti-inflammatory genes, reduces oxidative stress in neural tissue, and upregulates BDNF and nerve growth factor, supporting neurotrophic signaling.

Dihexa Component

Dihexa is derived from Angiotensin IV and is a potent agonist of the HGF (Hepatocyte Growth Factor) / c-Met receptor system in the brain. Activation of this pathway promotes dendritic spine formation, synaptic plasticity, and long-term potentiation, processes central to memory formation and retrieval.

Synergy

The combination provides simultaneous anti-neuroinflammatory support (GHK-Cu) and pro-synaptogenic activity (Dihexa), addressing both the maintenance environment and the structural plasticity of synapses.

Research Protocols

Administration

Intranasal as directed by vendor. 1–3 drops per nostril, allowing absorption through olfactory mucosa.

Cycle

Dihexa is extremely potent, very low doses are active. Standard cycles for Dihexa: 2–4 weeks on with 4 weeks off. GHK-Cu can be used longer term. Follow vendor guidance.

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Storage & Handling

Refrigerate at 2–8°C. Protect from light. Use within vendor-specified window after opening.


References

  • [1]See individual entries: GHK-Cu, Dihexa for component-specific references.
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Verified Scientific Data Last audited:
Data Sources & External References
Source: peer-reviewed literature  ·  Domain: ascendpeptide.org
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