OFF-LABEL / COMPOUND

EnclomipheneActive: Enclomiphene Citrate

Quick reference: Typical dose: 12.5 to 25 mg orally once daily. Some protocols dose every other day.

Fast facts

Active
Enclomiphene Citrate
Maker
Compounded / investigational
FDA Approval
Not approved as finished product
Half-life
~10 hours
Form
Oral capsule, typically 12.5 mg or 25 mg. Compounded by 503A pharmacies.
Indication
Not FDA-approved as a standalone product. Compounded oral formulations are prescribed off-label as an alternative to exogenous testosterone for men who wish to preserve fertility while raising endogenous T.

Dose schedule

Typical dose: 12.5 to 25 mg orally once daily. Some protocols dose every other day.

Recommended monitoring

Total testosterone, LH, FSH at 6 to 8 weeks. Sensitive E2 if symptoms warrant.

Clinical notes

Restoration approach rather than replacement. Effective primarily for men with functional secondary hypogonadism who retain testicular response to LH.

Open Enclomiphene Citrate Calculator → Compare testosterone ester schedules side by side

Frequently asked

What is the typical dose schedule for Enclomiphene?
Typical dose: 12.5 to 25 mg orally once daily. Some protocols dose every other day.
What is the half-life of Enclomiphene Citrate?
Enclomiphene has a half-life of approximately ~10 hours.
What monitoring labs are recommended on Enclomiphene?
Total testosterone, LH, FSH at 6 to 8 weeks. Sensitive E2 if symptoms warrant.
Is Enclomiphene the same as compounded enclomiphene citrate?
Enclomiphene is a finished FDA-approved drug product with consistent quality control. Compounded enclomiphene citrate produced by 503A or 503B pharmacies contains the same active ester but is not held to identical manufacturing standards. Verify the Certificate of Analysis when using a compound.
Is Enclomiphene a controlled substance?
Enclomiphene is not a controlled substance in the United States. A standard prescription is required for clinical use.

Related

For research informational use only. Not medical advice. Enclomiphene is a registered trademark of Compounded / investigational. Consult a qualified healthcare provider before any clinical decision. ASCEND, ascendpeptide.org