FDA-APPROVED BRAND
Mounjaro Dose Calculator and Titration ScheduleActive ingredient: Tirzepatide
Quick answer: Mounjaro (tirzepatide) titrates from 2.5 mg at week 1 to a 15 mg maintenance dose once weekly subcutaneously.
Fast facts
Active
Tirzepatide
Maker
Eli Lilly
FDA Approval
2022
Indication
Type 2 diabetes glycemic control
Form
Single-dose subcutaneous pen, 2.5 / 5 / 7.5 / 10 / 12.5 / 15 mg
Titration schedule
| Phase | Dose | Frequency | Route |
|---|---|---|---|
| Week 1-4 | 2.5 mg | 1 pen / week | SC |
| Week 5-8 | 5 mg | 1 pen / week | SC |
| Week 9-12 | 7.5 mg | 1 pen / week | SC |
| Week 13-16 | 10 mg | 1 pen / week | SC |
| Week 17-20 | 12.5 mg | 1 pen / week | SC |
| Week 21+ | 15 mg | 1 pen / week | SC |
Efficacy in clinical trials
SURPASS trial program: HbA1c reduction 2.0 to 2.5 percentage points at maintenance dose
Side effects timeline
GI events similar to GLP-1 mono-agonists. The added GIP receptor activity does not appear to increase GI burden significantly.
Cost and access
~$1,000 / month US list price; T2D indication typically gets insurance coverage
Open Tirzepatide Dose Calculator → Compare GLP-1 titration schedules side by sideFrequently asked
What is the standard Mounjaro titration schedule?
Mounjaro starts at 2.5 mg once weekly and steps up over 24 weeks to a maintenance dose of 15 mg once weekly. The slow ramp reduces GI side effects.
How long does it take to reach the target Mounjaro dose?
6 titration steps of about four weeks each, so approximately 24 weeks (roughly 6 months) from the first injection to maintenance. Researchers can extend any single step if side effects are limiting.
What if I miss a dose of Mounjaro?
If a Mounjaro dose is missed and the next scheduled dose is more than two days away, take the missed dose as soon as possible. If less than two days remain, skip the missed dose and resume the schedule. Do not double up.
What are the common side effects of Mounjaro?
GI events similar to GLP-1 mono-agonists. The added GIP receptor activity does not appear to increase GI burden significantly.
Is Mounjaro the same as Mounjaro?
Mounjaro and Zepbound both contain tirzepatide. They differ only in FDA-approved indication and labeling: Mounjaro is approved for Type 2 diabetes; Zepbound is approved for chronic weight management. Dosing and titration are identical.
Related
For research informational use only. Not medical advice. Mounjaro is a registered trademark of Eli Lilly. Consult a qualified healthcare provider before any clinical decision. ASCEND, ascendpeptide.org