⚖ Head-to-Head · Sleep Peptides

DSIP vs Epithalon

Mechanism, half-life, dosing & research status compared side-by-side.

DSIP
Sleep & Neuropeptides
Not Approved
SleepNeuropeptidesStressRecovery
Delta Sleep-Inducing Peptide (DSIP) is a nine-amino-acid neuropeptide first isolated from rabbit thalamic venous blood in 1974 by Marcel Monnier and colleagues at the University of Basel. DSIP is unique among sleep-relat…
Full DSIP profile →
Epithalon
Longevity & Telomere
Not Approved
LongevityTelomereAnti-agingPineal
Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal gland bioregulator Epithalamin. It was developed by the St. Petersburg Institute of Biogerontology by Professor Vladimir Khavinso…
Full Epithalon profile →
Technical Specs Comparison
MetricDSIPEpithalon
Research Status Moderately Studied Extensively Studied
Molecular Weight 849 Da 390.3 Da
Half-Life 30-60 min (IV); 2-3 h (SC) ~30 min
Peak Time 30-45 min ~20–30 min
Typical Dose 100-500 mcg 5–10 mg
Frequency 3-5 nights/week Once daily × 10–20 days (cycle)
Route Subcutaneous, IV Subcutaneous / IV
Amino Acids 9 4
WADA Status Not Listed Not Listed
FDA Status Not Approved Not Approved
Stack Compatibility & Key Differences
DSIP and Epithalon are commonly stacked - rated synergistic in research protocols.
PK Plotter
Visualize Epithalon plasma levels → Plot →
Frequently Asked Questions
What is the difference between DSIP and Epithalon?
DSIP: Delta Sleep-Inducing Peptide (DSIP) is a nine-amino-acid neuropeptide first isolated from rabbit thalamic venous blood in 1974 by Marcel Monnier and colleagues at the University of Basel. DSIP is unique among sleep-relat… Epithalon: Epithalon (Epitalon) is a synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal gland bioregulator Epithalamin. It was developed by the St. Petersburg Institute of Biogerontology by Professor Vladimir Khavinso…
Can you stack DSIP and Epithalon?
DSIP and Epithalon are commonly stacked - rated synergistic in research protocols.
Which has a longer half-life, DSIP or Epithalon?
DSIP half-life: 30-60 min (IV); 2-3 h (SC). Epithalon half-life: ~30 min.
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Verified Scientific Data
All specifications on this page are sourced from peer-reviewed literature and primary research. Half-life values, dosing ranges, and mechanism data are cross-referenced against published studies. Last audited 2026-06-07.
● Peer-reviewed sources ● Audit timestamp: 2026-06-07 ● Data version: ASCEND Wiki 2026
Data sourced from ASCEND Wiki · DSIP profile · Epithalon profile · All comparisons
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