Healing & Repair

OTR-AC Dosing & Reconstitution Calculator

BPC-157 acetate formulated for oral delivery. Higher doses compensate for GI degradation; provides direct mucosal contact.

TL;DR - OTR-AC is an oral healing & repair compound typically dosed at 2 mg daily. No reconstitution is required.
2 mg
Start Dose
100 mg
Vial
Track OTR-AC in Protocol Tracker
Frequently Asked
How do I reconstitute OTR-AC?
OTR-AC is taken orally; no reconstitution required.
What is the recommended dose of OTR-AC?
A typical research dose is 2 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a OTR-AC vial?
A 100 mg vial reconstituted with 0 mL BAC water yields approximately 50 doses at 2 mg each.
Peptide Intelligence
What is OTR-AC?
OTR-AC is the community name for oral high-dose BPC-157 acetate. The peptide sequence is identical to injectable BPC-157 (GEPPPGKPADDAGLV) but is dosed at 2-5 mg orally rather than 250-500 µg subcutaneously to compensate for GI degradation and first-pass metabolism.
How does OTR-AC dosing differ from injectable BPC-157?
Oral BPC-157 requires approximately 4-10x higher doses than subcutaneous injection due to partial degradation by stomach acid and intestinal enzymes. A common oral dose is 2-5 mg once daily compared to 250-500 µg once or twice daily for injection. Despite lower systemic bioavailability, the oral route provides direct mucosal contact throughout the GI tract.
Why stack OTR-AC with GLP-1 peptides like Tirzepatide?
GLP-1 receptor agonists commonly cause GI side effects including nausea, gastroparesis, and mucosal irritation. OTR-AC addresses these via BPC-157's gastroprotective and pro-kinetic mechanisms; it accelerates gastric emptying recovery and reduces GI inflammation via nitric oxide and growth factor pathways distinct from GLP-1 signaling.
Data last reviewed 2026-10-05 · Methodology →
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