Other
OTR-AC Dosing & Reconstitution Calculator
Oral capsule or powder · no reconstitution · take on empty stomach
TL;DR - OTR-AC is an oral other compound typically dosed at 2 mg daily. No reconstitution is required.
2 mg
Start Dose
100 mg
Vial
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Frequently Asked
How do I reconstitute OTR-AC?
OTR-AC is taken orally; no reconstitution required.
What is the recommended dose of OTR-AC?
A typical research dose is 2 mg. Consult the ASCEND calculator for your specific vial concentration and draw volume.
How many doses are in a OTR-AC vial?
A 100 mg vial reconstituted with 0 mL BAC water yields approximately 50 doses at 2 mg each.
Peptide Intelligence
What is OTR-AC?
OTR-AC is the community name for oral high-dose BPC-157 acetate. The peptide sequence is identical to injectable BPC-157 (GEPPPGKPADDAGLV) but is dosed at 2–5 mg orally rather than 250–500 µg subcutaneously to compensate for GI degradation and first-pass metabolism.
How does OTR-AC dosing differ from injectable BPC-157?
Oral BPC-157 requires approximately 4–10x higher doses than subcutaneous injection due to partial degradation by stomach acid and intestinal enzymes. A common oral dose is 2–5 mg once daily compared to 250–500 µg once or twice daily for injection. Despite lower systemic bioavailability, the oral route provides direct mucosal contact throughout the GI tract.
Why stack OTR-AC with GLP-1 peptides like Tirzepatide?
GLP-1 receptor agonists commonly cause GI side effects including nausea, gastroparesis, and mucosal irritation. OTR-AC addresses these via BPC-157's gastroprotective and pro-kinetic mechanisms; it accelerates gastric emptying recovery and reduces GI inflammation via nitric oxide and growth factor pathways distinct from GLP-1 signaling.
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Data last reviewed 2026-06-09 · Methodology →
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