RECONSTITUTION GUIDE

How Much BAC Water for Snap-8 (Argireline)?

Quick answer: Add 2 mL of bacteriostatic water to a 5 mg Snap-8 (Argireline) vial. This yields a concentration of 2.5 mg/mL. A standard 1 mg research dose then requires 0.4 mL (40 IU on a 100-unit insulin syringe).

1 mg draw on a 100-unit insulin syringe
010203040506070809010040 IUascendpeptide.org

Concentration by BAC water volume

Concentration and 1 mg draw volume at common BAC water volumes for a 5 mg vial.

BAC waterConcentrationDose volumeDraw
1 mL 5 mg/mL 0.2 mL 20 IU
2 mL Standard 2.5 mg/mL 0.4 mL 40 IU
3 mL 1.67 mg/mL 0.6 mL 60 IU
5 mL 1 mg/mL 1 mL 100 IU

Dose volume at the standard 2.5 mg/mL concentration

How draw volume changes if you vary the dose at the standard 5 mg + 2 mL reconstitution.

DoseVolumeIU draw (100u)
0.5 mg 0.2 mL 20 IU
1 mg Std 0.4 mL 40 IU
1.5 mg 0.6 mL 60 IU
2 mg 0.8 mL 80 IU
3 mg 1.2 mL 120 IU

Reconstitution steps

  1. Wipe the top of both the Snap-8 (Argireline) vial and the bacteriostatic water vial with alcohol swabs.
  2. Draw 2 mL of bacteriostatic water into a sterile syringe.
  3. Inject the water slowly down the inside glass wall of the Snap-8 (Argireline) vial. Do not aim directly at the powder.
  4. Swirl gently until fully dissolved. Never shake.
  5. Refrigerate at 2–8°C protected from light. Allow to reach room temperature before each draw.

Supplies needed

Open Snap-8 (Argireline) Calculator → What is bacteriostatic water?

Frequently asked

How much BAC water do I add to a 5 mg Snap-8 (Argireline) vial?
For the standard ASCEND research protocol, add 2 mL of bacteriostatic water to a 5 mg Snap-8 (Argireline) vial. This yields 2.5 mg/mL.
What concentration does 2 mL BAC water give for 5 mg Snap-8 (Argireline)?
A 5 mg Snap-8 (Argireline) vial reconstituted with 2 mL of bacteriostatic water yields 2.5 mg/mL. A 1 mg dose then requires 0.4 mL (40 IU on a 100-unit insulin syringe).
Can I use sterile water instead of bacteriostatic water for Snap-8 (Argireline)?
Bacteriostatic water (0.9% benzyl alcohol) is preferred because it inhibits bacterial growth and allows multi-dose use of the reconstituted vial. Sterile water lacks preservative properties and accelerates peptide degradation once the vial is opened.
How long is Snap-8 (Argireline) stable once reconstituted with BAC water?
Most research peptides remain stable for approximately 28 days when reconstituted with bacteriostatic water and stored at 2–8°C protected from light. Refer to peptide-specific stability data for any deviation from this baseline.
What size insulin syringe should I use for Snap-8 (Argireline)?
For a 1 mg dose (40 IU draw), a 50-unit (0.5 mL) or 100-unit U-100 insulin syringe is appropriate.

Related

For research use only. Not medical advice. Consult a qualified healthcare provider before using any peptide compound. Reconstitution parameters cross-referenced with independent 3rd-party analytical laboratories. · ASCEND · ascendpeptide.org