Tesamorelin
Growth Hormone
Approved
Growth HormoneWeight ManagementFDA ApprovedBody Composition
Tesamorelin (Egrifta) is a GHRH analog modified with a trans-3-hexenoic acid group at the N-terminus, which protects against dipeptidyl peptidase IV (DPP-IV) enzymatic cleavage and significantly extends biological activi…
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Sermorelin
Growth Hormone
Compounding Only
Growth HormoneAnti-agingRecoverySleep
Sermorelin is a synthetic analog of the first 29 amino acids of endogenous GHRH, retaining full biological activity at the GHRH receptor. It was FDA approved (Geref) for GH deficiency in children from 1997 until its volu…
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Frequently Asked Questions
What is the difference between Tesamorelin and Sermorelin?
Tesamorelin: Tesamorelin (Egrifta) is a GHRH analog modified with a trans-3-hexenoic acid group at the N-terminus, which protects against dipeptidyl peptidase IV (DPP-IV) enzymatic cleavage and significantly extends biological activi… Sermorelin: Sermorelin is a synthetic analog of the first 29 amino acids of endogenous GHRH, retaining full biological activity at the GHRH receptor. It was FDA approved (Geref) for GH deficiency in children from 1997 until its volu…
Can you stack Tesamorelin and Sermorelin?
Tesamorelin has FDA approval; Sermorelin is research-only.
Which has a longer half-life, Tesamorelin or Sermorelin?
Tesamorelin half-life: ~26–38 min. Sermorelin half-life: ~10–20 min.