⚖ Head-to-Head · Systemic Repair Peptides

TB-500 vs Thymosin Alpha-1

Mechanism, half-life, dosing & research status compared side-by-side.

TB-500
Healing & Recovery
Not Approved
HealingRecoveryCardiacAnti-inflammatory
TB-500 is a synthetic fragment of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide found in virtually all human and animal cells. It is particularly concentrated in platelets and wound fluid, where it p…
Full TB-500 profile →
Thymosin Alpha-1
Immune Support
Not Approved (US)
Immune SupportAnti-agingAntiviralLongevity
Thymosin Alpha-1 (TA1) is a 28-amino acid peptide naturally secreted by thymic epithelial cells, commercially available as Thymalfasin (Zadaxin). It is approved as a pharmaceutical drug in over 35 countries (including Ch…
Full Thymosin Alpha-1 profile →
Technical Specs Comparison
MetricTB-500Thymosin Alpha-1
Research Status Extensively Studied Extensively Studied
Molecular Weight 4,963 Da 3,108 Da
Half-Life ~5 days ~2 hours
Peak Time ~2–4 hours ~1–2 hours
Typical Dose 2.5–5 mg 0.8–1.6 mg
Frequency 2–3× per week 2× weekly or daily
Route Subcutaneous Subcutaneous
Amino Acids 43 28
WADA Status Prohibited Not Listed
FDA Status Not Approved Not Approved (US)
Stack Compatibility & Key Differences
Both are active research compounds. See individual pages for full protocol data.
PK Plotter
Visualize TB-500 plasma levels → Plot →
Frequently Asked Questions
What is the difference between TB-500 and Thymosin Alpha-1?
TB-500: TB-500 is a synthetic fragment of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino acid peptide found in virtually all human and animal cells. It is particularly concentrated in platelets and wound fluid, where it p… Thymosin Alpha-1: Thymosin Alpha-1 (TA1) is a 28-amino acid peptide naturally secreted by thymic epithelial cells, commercially available as Thymalfasin (Zadaxin). It is approved as a pharmaceutical drug in over 35 countries (including Ch…
Can you stack TB-500 and Thymosin Alpha-1?
Both are active research compounds. See individual pages for full protocol data.
Which has a longer half-life, TB-500 or Thymosin Alpha-1?
TB-500 half-life: ~5 days. Thymosin Alpha-1 half-life: ~2 hours.
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Verified Scientific Data
All specifications on this page are sourced from peer-reviewed literature and primary research. Half-life values, dosing ranges, and mechanism data are cross-referenced against published studies. Last audited 2026-06-07.
● Peer-reviewed sources ● Audit timestamp: 2026-06-07 ● Data version: ASCEND Wiki 2026
Data sourced from ASCEND Wiki · TB-500 profile · Thymosin Alpha-1 profile · All comparisons
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